Research

Research with children and young people with cancer has allowed 5-year survival rates to climb from 10% in the 1970s to 85% in the current decade. It has been an essential part of cancer care since the beginning, and Yorkshire and the Humber has been at the heart of hundreds of clinical studies over the years. The cancer clinical network is committed to continuing to make access to clinical studies as equitable, accessible, and comprehensive as possible.

Research does not just involve new drugs or laboratories. Investigating how people feel, how side effects can be managed or prevented, how different cancers occur in different groups (and have different outcomes) are all areas which can and are researched. In order to make information available as rapidly as possible, the links below will take you to partner sites which aggregate the majority of research opportunities currently open.

Research Highlight

Yorkshire and Humber Children Teenage and Young Adult Delivery Network logo icon
The Reforms Project logo

The REFoRMS Project: Understanding Decision Making for RElapsed and REFractory RhabdoMyoSarcoma

Research Team:

Orange Leaf  Dr Bob Phillips
Purple Leaf  Dr Jess Morgan
Pink Leaf  Dr Gemma Bryan
Dark Blue Leaf  Lucy Beresford
Light Blue Leaf  Connor Evans

REFoRMS is a research project run at the Centre for Reviews and Dissemination at the University of York. REFoRMS focus on a form of childhood cancer called rhabdomyosarcoma (RMS), when the disease has not responded to treatment (refractory) or has come back after treatment (relapsed). REFoRMS aim to bring together all studies of new or emerging treatments (early phase studies) for children and young people with relapsed and refractory RMS. It also aims to understand how families make decisions in this situation, and how they can be best supported in this.

The REFoRMS website is here: https://www.cclg.org.uk/our-research-projects/reforms-project and the project Twitter account is @REFoRMS_Rhabdo.

Color brushstroke oil or acrylic paint design element - transparent background
pcor-1

PCOR (Patient Centred Outcomes Research)

Patient centred outcomes research (PCOR) conduct TYA specific research with one research programme running currently and one recently finished. Please their website for more information: https://pcor.org.uk/tya/

Color brushstroke oil or acrylic paint design element - transparent background
Strong_AYA_logo (1)

Strong-AYA

Programme Team:

Orange Leaf  Dan Stark
Purple Leaf  Oana Lindner
Pink Leaf  Richard Feltbower
Dark Blue Leaf  Emily Connearn
Light Blue Leaf  Nicola Hughes
Orange leaf  Rob Carter
Purple leaf  Louise Hick
Yellow leaf  Faatimah Patel

Strong-AYA is a European network aiming to improve healthcare services, research and outcomes for adolescents and young adults (AYA’s) with cancer, defined as people aged between 15-39 years at cancer diagnosis. AYAs with cancer are distinct from the paediatric and the older adult cancer populations. Around half of AYA with cancer currently report unmet informational and service needs, impacting their survival rates, late effects of cancer and its treatment, mental health and recovery to participate in the society. Within STRONG-AYA, we will set up a healthcare research ecosystem to develop data-driven, interactive policy and visualization tools to bring novel insights into AYA healthcare.

Strong-AYA website - https://strongaya.eu/

Color brushstroke oil or acrylic paint design element - transparent background
TYA_logo

STARS (Social Integration After a Cancer Diagnosis in Adolescents and Young Adults (AYA))

This project explored social outcomes after a cancer diagnosis. It is now in the write-up and dissemination phase. It was funded by the Economic and Social Research Council (ESRC ES/S00565X/1). It began in September 2019 and ended in August 2023. Follow them on Twitter/Instagram @YoungCancerLife for updates, news, and discussions on this project.

Partner Organisations

Yorkshire and Humber Children Teenage and Young Adult Delivery Network logo icon

CCLG

Yorkshire and Humber Children Teenage and Young Adult Delivery Network logo icon

https://www.cclg.org.uk/

CCLG research is focused only on cancers affecting children and young people. Through their funding of world-class research, they aim to deepen understanding and foster collaborations to support some of the most innovative and ground-breaking research into childhood cancer.

Color brushstroke oil or acrylic paint design element - transparent background

For professionals

Yorkshire and Humber Children Teenage and Young Adult Delivery Network logo icon

ECMC (Experimental Cancer Medicine Centre) Trial Finder